Serum ferritin has correlation with HbA1c in type 2 diabetic patients.

Momeni, Ali. and Behradmanesh, Mohammad Saeed. and Kheiri, Soleiman. and Abasi, Fatemeh. (2015) Serum ferritin has correlation with HbA1c in type 2 diabetic patients. Advanced biomedical research, 4. p. 74. ISSN 2277-9175

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Abstract

BACKGROUND Serum C-reactive protein (CRP) and ferritin are two acute phase reactants. CRP may be related to metabolic syndrome and ferritin which in turn could cause resistance to insulin and dysfunction of b cells of pancreases. The aim of the study was the evaluation of the relationship of these two acute phase reactants with some indices of diabetic control. MATERIALS AND METHODS In a quasi-experimental study, 67 patients with type 2 diabetes, serum CRP, ferritin, Fasting Blood Sugar (FBS), post prandial BS, Hemoglobin A1c (HbA1c), triglyceride, Low Density Lipoprotein Cholesterol (LDL) and High Density Lipoprotein cholesterol (HDL) were checked before and 3 months after the control of hyperglycemia and hyperlipidemia. RESULTS The mean age of the patients was 56.5 ± 9.7 (30 to 82) years. There was no significant difference between CRP before and after study; however, serum ferritin significantly decreased after study with control of hyperglycemia. FBS, 2 hours post-prandial blood sugar (2hppBS), HbA1c and triglyceride of patients decreased significantly after control of hyperglycemia and hyperlipidemia (P < 0.05); however, HDL and LDL cholesterol didn't change (P > 0.05). CONCLUSION Based on our results, serum ferritin decreased after decline of patients' blood sugar, so might be we used it as one of the diabetes control indices for diabetic patients.

Item Type: Article
Uncontrolled Keywords: C-reactive protein; diabetes control indices; ferritin
Subjects: WD Nutrition Disease and metabolic diseases
QU Biochemistry
Divisions: Faculty of Medicine > Department of Clinical Sciences > Department of Internal Medicine
Faculty of Medicine > School of Medicine
Reserach Vice-Chancellar Department > Clinical Biochemistry Research Center
Depositing User: zahra bagheri .
Date Deposited: 26 Jul 2017 04:42
Last Modified: 17 Feb 2018 06:25
URI: http://eprints.skums.ac.ir/id/eprint/1783

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