Honey versus diphenhydramine for post-tonsillectomy pain relief in pediatric cases: a randomized clinical trial.

Amani, Soroush. and Kheiri, Soleiman. and Ahmadi, Ali. (2015) Honey versus diphenhydramine for post-tonsillectomy pain relief in pediatric cases: a randomized clinical trial. Journal of clinical and diagnostic research : JCDR, 9 (3). SC01-4. ISSN 2249-782X

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Abstract

INTRODUCTION Tonsillectomy is one of the most common surgeries done worldwide and often the first one a child sustains. Pain relief after tonsillectomy is helpful for oral feeding after surgery. Acetaminophen and diphenhydramine have been conventionally used for reducing pain. This study was conducted to compare the effect of honey and diphehydramine on pain relief after tonsillectomy. MATERIALS AND METHODS For this randomized clinical trial study, 120 patients of 5 to 12 years undergoing tonsillectomy were recruited. The patients were divided into four groups randomly. After tonsillectomy and beginning of eating, Group A took 5cc honey alone every hour, Group B was given 5 cc 50% honey (mixed with water) every hour, group C was treated with 1mg/kg diphenhydramine every 6 hours and group D was observed without any intervention. In all patients, severity of the pain was evaluated by ocher questionnaire at recovery, and 3, 6, 12 and 24 hours after surgery. The data were analyzed using ANOVA and the repeated measures ANOVA (SPSS version 17). RESULTS The repeated ANOVA showed a significant decreasing trend of pain scores during the study for both pain scales (p <0.05), but the rate of trend was similar between the four groups (p > 0.05). No statistically significant difference in pain was detected among the groups. CONCLUSION Although honey can help the pain decrease, more research is supported for confirmation of this effect.

Item Type: Article
Uncontrolled Keywords: Curative agent; Pediatric cases; Treatment
Subjects: WS Pediatrics
QV pharmacology > QV 752 Pharmacognosy
Divisions: Faculty of Health > Department of Epidemiology
Depositing User: Users 1 not found.
Date Deposited: 26 Jul 2017 03:40
Last Modified: 19 Feb 2018 05:26
URI: http://eprints.skums.ac.ir/id/eprint/1776

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