Comparison of non-electrophoresis grade with electrophoresis grade BIS in NIPAM polymer gel preparation.

Khodadadi, R. and Khajeali, A. and Farajollahi, A.R. and Hajalioghli, P. and Raeisi, N. (2015) Comparison of non-electrophoresis grade with electrophoresis grade BIS in NIPAM polymer gel preparation. BioImpacts : BI, 5 (3). pp. 129-33. ISSN 2228-5652

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Abstract

INTRODUCTION The main objective of this study was to investigate the possibility of replacing electrophoresis cross-linker with non-electrophoresis N, N'-methylenebisacrylamide (BIS) in N-isopropyl acrylamide (NIPAM) polymer gel and its possible effect on dose response. METHODS NIPAM polymer gel was prepared from non-electrophoresis grade BIS and the relaxation rate (R2) was measured by MR imaging after exposing the gel to gamma radiation from Co-60 source. To compare the response of this gel with the one that contains electrophoresis grade BIS, two sets of NIPAM gel were prepared using electrophoresis and non-electrophoresis BIS and irradiated to different gamma doses. RESULTS It was found that the dose-response of NIPAM gel made from the non-electrophoresis grade BIS is coincident with that of electrophoresis grade BIS. CONCLUSION Taken all, it can be concluded that the non-electrophoresis grade BIS not only is a suitable alternative for the electrophoresis grade BIS but also reduces the cost of gel due to its lower price.

Item Type: Article
Uncontrolled Keywords: Cross linker agent; N, N′-Methylenebisacrylamide (BIS); NIPAM gel; Polymer gel dosimetry
Subjects: QT physiology
Divisions: Faculty of Medicine
Depositing User: Users 1 not found.
Date Deposited: 25 Jul 2017 07:48
Last Modified: 25 Jul 2017 07:48
URI: http://eprints.skums.ac.ir/id/eprint/1720

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