The effects of cognitive behavioral therapy and drug therapy on quality of life and symptoms of patients with irritable bowel syndrome

Dehkordi, A. and Solati, K. (2017) The effects of cognitive behavioral therapy and drug therapy on quality of life and symptoms of patients with irritable bowel syndrome. Journal of Advanced Pharmaceutical Technology and Research, 8 (2). pp. 67-72.

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Abstract

Psychotherapy and drug therapy are considered useful in quality of life (QOL) and symptoms of patients with irritable bowel syndrome (IBS). The aim of this study was to examine the effects of cognitive behavioral therapy (CBT) associated with drug therapy in comparison to drug therapy alone on the QOL and symptoms of IBS patients with diarrhea predominance. This study was a randomized clinical trial on 64 IBS patients. The patients were selected according to Rome III criteria and were assigned into two groups. Bowel symptom severity and frequency scale and QOL-IBS were used to investigate the patients' symptoms. The first group underwent CBT with medication therapy, and the second group received only medication. Data were analyzed using analysis of multiple covariance. The two groups showed a significant difference in the QOL-IBS in posttreatment and follow-up stages (P < 0.05). There were significant differences in the severity and frequency of IBS symptoms between the two groups after the intervention (P < 0.05). However, no significant difference was observed at follow-up stage between the two groups (P > 0.05). CBT accompanied by drug therapy can be useful for IBS patients with diarrhea predominance. However, discontinuing this treatment may lead to recurrence of the symptoms. © 2017 Journal of Advanced Pharmaceutical Technology & Research | Published by Wolters Kluwer -Medknow.

Item Type: Article
Additional Information: cited By 0
Uncontrolled Keywords: Cognitive therapy, drug therapy, irritable bowel syndrome, quality of life symptoms
Subjects: WI Digestive System
WM Psychiatry
QV pharmacology > QV 704 Pharmaceutics
Divisions: Faculty of Medicine > Department of Clinical Sciences > Department of Psychiatry
Faculty of Nursing and Midwifery > Department of Nursing - Medical Surgical
Depositing User: zahra bagheri .
Date Deposited: 20 Jun 2017 08:32
Last Modified: 20 Jun 2017 08:32
URI: http://eprints.skums.ac.ir/id/eprint/156

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