Evaluation of mouse embryos produced in vitro after electromagnetic waves exposure; Morphometric study.

Rostamzadeh, Ayoob. and Mohammadi, Mohsen. and Ahmadi, Reza. and Nazari, Afshin. and Ghaderi, Omar. and Anjomshoa, Maryam. (2016) Evaluation of mouse embryos produced in vitro after electromagnetic waves exposure; Morphometric study. Electronic physician, 8 (1). pp. 1701-10. ISSN 2008-5842

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Abstract

INTRODUCTION Today, the use of electromagnetic waves in medical diagnostic devices, such as magnetic resonance imaging (MRI), has increased, and many of its biological effects have been reported. The aim of the present study was to assess the biological effects of 1.5 Tesla (T) magnetic resonance imaging (MRI) on fertility and reproductive parameters. METHODS Eighty adult male and female NMRI mice (NMRI: Naval Medical Research Institute) of age 6-8 weeks were studied and randomly divided into two study and control groups. After confirmation of pregnancy, the mice in the study group were exposed to the MRI (1.5 T) machine's waves over the next three weeks, once a week for 36 minutes. One day and thirty-five days after the last radiation, the mice were killed in order to do the in vitro fertilization (IVF) by neck beads' displacement and the impact on the evolution of embryos, and its quality was studied. Data were analyzed using SPSS version 20 and the significance level of less than 0.05 was considered. RESULTS Embryo morphometry showed that the total diameter and the cytoplasm diameter of the study group embryos suffered significant reduction compared to the control group, 1 day after the last irradiation (p < 0.05), but the diameter of the perivitelline space of this group's embryos had a significant increase (p < 0.05). The qualitative results during 35 days after irradiation showed that morphologically parameters of the embryos in the study group had no significant differences from the control group. CONCLUSION Exposure to MRI irradiation can transiently disturb the development of mouse embryos and fertility, but these effects are reversible 35 days after the last irradiation.

Item Type: Article
Uncontrolled Keywords: MRI (Magnetic resonance imaging); embryo morphometry; fertility
Subjects: WN Radiology . Diagnostic Imaging
WP Gynecology
Divisions: Faculty of Medicine > Basic Sciences Academic Groups > Department of Anatomy (Histology and Embryology
Depositing User: zahra bagheri .
Date Deposited: 18 Jul 2017 03:11
Last Modified: 18 Feb 2018 10:25
URI: http://eprints.skums.ac.ir/id/eprint/1464

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