Copper-doped 45S5 bioglass nanoparticles for tissue engineering applications: A comparative study

Barabadi, Z. and Sharifi, E. and Azami, M. and Ai, J. (2016) Copper-doped 45S5 bioglass nanoparticles for tissue engineering applications: A comparative study. BIOINTERFACE RESEARCH IN APPLIED CHEMISTRY, 6 (3, SI). pp. 1185-1189.

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Abstract

In this study, 45S5 bioglass and copper-doped 45S5 bioglass nanoparticles were prepared using sol gel technique, copper doped in the structure of 45S5 bioglass at three concentration to determine a biocompatible and effective concentration that is appropriate for Tissue engineering application. The prepared nanoparticles were analyzed using Fourier Transform Infrared Spectroscopy (FTIR), as we ray diffraction (XRD) analysis and EDAX. The nanostructures of the prepared samples were analyzed using Scanning Electron Microscopy (SEM). The effects of the doped copper were studied on the cytotoxicity of the 45S5 bioglass nanoparticles structu indirectly using MTT analysis by L929 mouse fibroblast cells. It was shown that increasing the concentration of copper can decrease the glass transition temperatures, and affecting the structure of 45S5 bioglass, although increasing the copper content were cyto assay revealed 1% copper is suitable for cell viability and is no toxic

Item Type: Article
Uncontrolled Keywords: 45S5 Bioglass nanoparticles; copper; cell viability
Subjects: QT physiology
Divisions: Reserach Vice-Chancellar Department > Cellular and Molecular Research Center
Depositing User: zahra bagheri .
Date Deposited: 16 Jul 2017 05:29
Last Modified: 17 Jul 2017 03:03
URI: http://eprints.skums.ac.ir/id/eprint/1175

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